Textbook of Biochemistry with Clinical Correlations: Glycolysis and related reactions Flashcards


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created 10 years ago by kelley2wisc
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updated 10 years ago by kelley2wisc
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1

Hexokinase

Glucose->glucose 6-phosphate

Inhibits: G6P
Stimulates: none

2

Glucokinase

Glucose-->glucose 6 phosphate

Inhibits: Induction (Liver)
Stimulates: Induction (Liver)

3

G 6 Phosphatase

Glucose 6 phosphate-->Glucose

Inhibits: Induction (Liver)
Stimulates: Induction (Liver)

4

Phosphoglucose isomerase

Glucose 6 phosphate<->Fructose 6 phosphate

5

PFK1

Fructose 6 Phosphate-->Fructose 1,6 Biphosphate

Inhibits: citrate, H+, ATP
Stimulates: F26-BP, AMP

6

PFK2

Fructose 6 Phosphate <-> F 2-6 BP

Inhibits: PKA (liver)
Stimulates: PKA (heart)

7

F-1,6 Bpase

Fructose 1,6 Biphosphate--> Fructose 6 Phosphate

Inhibits: PKA (muscle), AMP, F26BP, Induction
Stimulates: Induction, PKA (Liver)

8

FBPA

Fructose 1,6 Biphosphate<->Glyceraldehyde 3 Phosphate

9

GA3PD

Glyceraldehyde 3 Phosphate<->1,3 Biphosphoclycerate

10

PGK

1,3 Biphosphoglycerate<->3-phosphoglycerate

11

PGYM

3 Phosphoglycerate<-> 2 phosphoglycerate

12

Enolase

2 phosphoglycerate<->phosphoenolpyruvate

13

Pyruvate Kinase

phosphoenolpyruvate--> pyruvate

Inhibits: acetyl CoA, alanine, ATP (allosteric), PKA: covalent (Liver), Induction (Liver)
Stimulates: F16BP, Induction (Liver)

14

Lactate Dehydrogenase

Pyruvate<->Lactate

15

PCK

Oxaloacetate--> phosphenolpyruvate
Oxaloacetate (TCA)-->phosphenolpyruvate

Inhibits: Induction
Stimulates: Induction

16

Glycerol Kinase

Glycerol-->glycerol 3-phosphate

17

GL3PD

DHAP<-> Glycerol 3 Phosphate

18

TPA

Glyceraldehyde 3 Phosphate <-> DHAP

19

Fructose Kinase

Fructose -->Fructose 1 Phosphate

20

Aldolase

Fructose 1 Phosphate--> Glyceraldehyde

21

Triose Kinase

Glyceraldyde--> Glyceraldehyde 3 phosphate