1) The smallest cell structure that would most likely be visible with
a standard (not super- resolution) research-grade light microscope is
a _____.
A) mitochondrion
B) microtubule
C) ribosome
D) microfilament
A
2) The advantage of light microscopy over electron microscopy is that
_____.
A) light microscopy provides for higher magnification than
electron microscopy
B) light microscopy provides for higher resolving power than
electron microscopy C) light microscopy allows one to view dynamic
processes in living cells
D) light microscopy provides higher
contrast than electron microscopy
C
3) In the fractionation of homogenized cells using centrifugation,
the primary factor that determines whether a specific cellular
component ends up in the supernatant or the pellet is the
_____.
A) relative solubility of the component
B) size and
weight of the component
C) percentage of carbohydrates in the
component
D) presence or absence of lipids in the component
B
5) What technique would be most appropriate to use to observe the
movements of condensed chromosomes during cell division?
A)
standard light microscopy
B) scanning electron microscopy
C) transmission electron microscopy
A
7) All of the following are part of a prokaryotic cell EXCEPT _____.
A) a cell wall
B) a plasma membrane
C) ribosomes
D) an endoplasmic reticulum
D
8) Cell size is limited by _____.
A) the number of proteins
within the plasma membrane
B) the surface area of mitochondria in the cytoplasm
C) surface to volume ratios
D) the size of the endomembrane system
C
9) Which of the following is a major difference between prokaryotic cells and eukaryotic cells?
A) Prokaryotes have cells while eukaryotes do not.
B)
Eukaryotic cells have more intracellular organelles than
prokaryotes.
C) Prokaryotes are not able to carry out aerobic
respiration, relying instead on anaerobic metabolism.
D) Prokaryotes are generally larger than eukaryotes.
B
10) You have a cube of modeling clay in your hands. Which of the
following changes to the shape of this cube of clay will decrease its
surface area relative to its volume?
A) Pinch the edges of the
cube into small folds.
B) Flatten the cube into a pancake shape.
C) Round the clay up into a sphere.
D) Stretch the cube into
a long, shoebox shape.
C
11) Prokaryotes are classified as belonging to two different domains. What are the domains?
A) Bacteria and Eukarya
B) Bacteria and Archaea
C)
Archaea and Protista
D) Bacteria and Protista
B
12) Which structure is common to plant and animal cells?
A) chloroplast
B) central vacuole
C) mitochondrion
D) centriole
C
13) Which of the following is present in a prokaryotic cell?
A) mitochondrion
B) ribosome
C) chloroplast
D) ER
B
14) In a bacterium, we will find DNA in _____.
A) a membrane-enclosed nucleus
B) mitochondria
C) the nucleoid
D) ribosomes
C
15) Which organelle or structure is absent in plant cells?
A) mitochondria
B) microtubules
C) centrosomes
D) peroxisomes
C
16) What is the function of the nuclear pore complex found in
eukaryotes?
A) It regulates the movement of proteins and RNAs
into and out of the nucleus.
B) It synthesizes the proteins
required to copy DNA and make mRNA.
C) It selectively transports
molecules out of the nucleus, but prevents all inbound molecules from
entering the nucleus.
D) It assembles ribosomes from raw
materials that are synthesized in the nucleus.
A
17) Which of the following macromolecules leaves the nucleus of a
eukaryotic cell through pores in the nuclear membrane?
A)
DNA
B) amino acids
C) mRNA
D) phospholipids
C
18) Which of the following statements correctly describes some aspect
of protein secretion from prokaryotic cells?
A) Prokaryotes
cannot secrete proteins because they lack an endomembrane
system.
B) The mechanism of protein secretion in prokaryotes is
probably the same as that in eukaryotes.
C) Proteins secreted by prokaryotes are synthesized on ribosomes bound to the cytoplasmic surface of the plasma membrane.
D) Prokaryotes cannot secrete proteins because they lack ribosomes.
C
19) Large numbers of ribosomes are present in cells that specialize
in producing which of the following molecules?
A) lipids
B) glycogen
C) proteins
D) nucleic acids
C
21) A cell with a predominance of free ribosomes is most likely _____.
A) primarily producing proteins for secretion
B) primarily
producing proteins in the cytosol
C) constructing an extensive
cell wall or extracellular matrix
D) enlarging its vacuole
B
22) Which organelle often takes up much of the volume of a plant cell?
A) lysosome
B) vacuole
C) Golgi apparatus
D) peroxisome
B
23) A cell with an extensive area of smooth endoplasmic reticulum is specialized to _____.
A) play a role in storage
B) synthesize large quantities of
lipids
C) actively export protein molecules
D) import and export protein molecules
B
24) Which structure is NOT part of the endomembrane system?
A) nuclear envelope
B) chloroplast
C) Golgi apparatus
D) plasma membrane
B
27) Which structure is the site of the synthesis of proteins that may be exported from the cell?
A) rough ER
B) plasmodesmata
C) Golgi vesicles
D) free cytoplasmic ribosomes
A
29) The liver is involved in detoxification of many poisons and
drugs. Which of the following structures is primarily involved in this
process and, therefore, abundant in liver cells?
A) rough
ER
B) smooth ER
C) Golgi apparatus
D) nuclear envelope
B
30) Which of the following produces and modifies polysaccharides that will be secreted?
A) lysosome
B) mitochondrion
C) Golgi apparatus
D) peroxisome
C
31) What is the most likely pathway taken by a newly synthesized
protein that will be secreted by a cell?
A) ER → Golgi →
nucleus
B) Golgi → ER → lysosome
C) ER → Golgi → vesicles that fuse with plasma membrane
D)
ER → lysosomes → vesicles that fuse with plasma membrane
C
32) Asbestos is a material that was once used extensively in construction. One risk from working in a building that contains asbestos is the development of asbestosis caused by the inhalation of asbestos fibers. Cells will phagocytize asbestos, but are not able to degrade it. As a result, asbestos fibers accumulate in _____.
A) mitochondria
B) ribosomes
C) peroxisomes
D) lysosomes
D
33) Which of the following is NOT true? Both chloroplasts and mitochondria _____.
A) have their own DNA
B) have multiple membranes
C) are
part of the endomembrane system
D) are capable of reproducing themselves
C
34) Which organelle is the primary site of ATP synthesis in eukaryotic cells?
A) lysosome
B) mitochondrion
C) Golgi apparatus
D) peroxisome
B
35) Thylakoids, DNA, and ribosomes are all components found in _____.
A) chloroplasts
B) mitochondria
C) lysosomes
D) nuclei
A
36) In a plant cell, DNA may be found _____.
A) only in the
nucleus
B) only in the nucleus and chloroplasts
C) in the
nucleus, mitochondria, and chloroplasts
D) in the nucleus,
mitochondria, chloroplasts, and peroxisomes
C
37) In a liver cell detoxifying alcohol and some other poisons, the
enzymes of the peroxisome remove hydrogen from these molecules and
_____.
A) combine the hydrogen with water molecules to generate
hydrogen peroxide
B) use the hydrogen to break down hydrogen peroxide
C) transfer the hydrogen to the mitochondria
D) transfer the
hydrogen to oxygen molecules to generate hydrogen peroxide
D
38) The evolution of eukaryotic cells most likely involved
_____.
A) endosymbiosis of an aerobic bacterium in a larger host
cell—the endosymbiont evolved into mitochondria
B) anaerobic
archaea taking up residence inside a larger bacterial host cell to
escape toxic oxygen—the anaerobic bacterium evolved into
chloroplasts
C) an endosymbiotic fungal cell evolving into the
nucleus
D) acquisition of an endomembrane system and subsequent
evolution of mitochondria from a portion of the Golgi
A
39) Where are proteins produced other than on ribosomes free in the
cytosol or ribosomes attached to the ER?
A) in the extracellular
matrix
B) in the Golgi apparatus
C) in mitochondria
D) in the nucleolus
C
40) Suppose a cell has the following molecules and structures:
enzymes, DNA, ribosomes, plasma membrane, and mitochondria. It could
be a cell from _____.
A) a bacterium
B) an animal but not a plant
C) nearly any eukaryotic organism
D) a plant but not an animal
C
41) Cyanide binds with at least one molecule involved in producing
ATP. If a cell is exposed to cyanide, most of the cyanide will be
found within the _____.
A) mitochondria
B) peroxisomes
C) lysosomes
D) endoplasmic reticulum
A
42) Suppose a young boy is always tired and fatigued, suffering from
a metabolic disease. Which of the following organelles is most likely
involved in this disease?
A) lysosomes
B) Golgi apparatus
C) ribosomes
D) mitochondria
D
43) Motor proteins provide for molecular motion in cells by
interacting with what types of cellular structures?
A) membrane
proteins of the inner nuclear envelope
B) free ribosomes and
ribosomes attached to the ER
C) components of the cytoskeleton
D) cellulose fibers in the
cell wall
C
45) Vinblastine, a drug that inhibits microtubule polymerization, is
used to treat some forms of cancer. Cancer cells given vinblastine
would be unable to _____.
A) form cleavage furrows during cell
division
B) migrate by amoeboid movement
C) separate chromosomes during cell division
D) maintain the shape of the nucleus
C
46) Amoebae move by crawling over a surface (cell crawling), which
involves _____.
A) growth of actin filaments to form bulges in
the plasma membrane
B) setting up microtubule extensions that
vesicles can follow in the movement of cytoplasm
C) reinforcing the pseudopod with intermediate filaments
D)
cytoplasmic streaming
A
49) Spherocytosis is a human blood disorder associated with a
defective cytoskeletal protein in the red blood cells (RBCs). What do
you suspect is the consequence of such a defect?
A) abnormally
shaped RBCs
B) an insufficient supply of ATP in the RBCs
C) an insufficient supply of oxygen-transporting proteins in the RBCs
D) adherence of RBCs to blood vessel walls, causing plaque formation
A
50) Cytochalasin D is a drug that prevents actin polymerization. A
cell treated with cytochalasin D will still be able to _____.
A)
divide in two
B) contract muscle fibers
C) extend pseudopodia
D) move vesicles within a cell
D
51) Cells require which of the following to form cilia or flagella?
A) tubulin
B) laminin
C) actin
D) intermediate filaments
A
52) Which of the following statements about the cytoskeleton is
true?
A) The cytoskeleton of eukaryotes is a static structure
most resembling scaffolding used at construction sites.
B)
Although microtubules are common within a cell, actin filaments are
rarely found outside of the nucleus.
C) Movement of cilia and
flagella is the result of motor proteins causing microtubules to move
relative to each other.
D) Chemicals that block the assembly of
the cytoskeleton would have little effect on a cell's response to
external stimuli.
C
53) The cell walls of bacteria, fungi, and plant cells and the
extracellular matrix of animal cells are all external to the plasma
membrane. Which of the following is a characteristic common to all of
these extracellular structures?
A) They must block water and
small molecules to regulate the exchange of matter and energy with
their environment.
B) They must provide a rigid structure that maintains an
appropriate ratio of cell surface area to volume.
C) They are
constructed of polymers that are synthesized in the cytoplasm and
then transported out of the cell.
D) They are composed of a mixture of lipids and nucleotides.
C
54) A mutation that disrupts the ability of an animal cell to add
polysaccharide modifications to proteins would most likely cause
defects in its _____.
A) nuclear matrix and extracellular
matrix
B) mitochondria and Golgi apparatus
C) Golgi apparatus and extracellular matrix
D) nuclear pores and secretory vesicles
C
56) Plasmodesmata in plant cells are most similar in function to
which of the following structures in animal cells?
A)
desmosomes
B) gap junctions
C) extracellular matrix
D) tight junctions
B
57) Ions can travel directly from the cytoplasm of one animal cell to
the cytoplasm of an adjacent cell through _____.
A)
plasmodesmata
B) tight junctions
C) desmosomes
D) gap junctions
D
58) In plant cells, the middle lamella _____.
A) allows adjacent
cells to adhere to one another
B) prevents dehydration of
adjacent cells
C) maintains the plant's circulatory
system
D) allows for gas and nutrient exchange among adjacent cells
A
59) Where would you expect to find tight junctions?
A) in the
epithelium of an animal's stomach
B) between the smooth
endoplasmic reticulum and the rough endoplasmic reticulum
C) between plant cells in a woody plant
D) in the plasma
membrane of prokaryotes
A
61) Gaucher disease is the most common of lipid storage diseases in humans. It is caused by a deficiency of an enzyme necessary for lipid metabolism. This leads to a collection of fatty material in organs of the body including the spleen, liver, kidneys, lungs, brain, and bone marrow.
Using your knowledge of the structure of eukaryotic cells,
identify the statement below that best explains how internal
membranes and the organelles of cells would be involved in Gaucher
disease.
A) The mitochondria are most likely defective and do
not produce adequate amounts of ATP needed for cellular respiration.
B) The rough endoplasmic reticulum contains too many ribosomes
which results in an overproduction of the enzyme involved in
carbohydrate catalysis.
C) The lysosomes lack sufficient amounts
of enzymes necessary for the metabolism of lipids.
D) The Golgi apparatus produces vesicles with faulty membranes that leak their contents into the cytoplasm of the cell.
C