pregnancy and preterm labor

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created 9 days ago by Akosua_Ruby
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Pharmacology
Chapters 49, 50
updated 9 days ago by Akosua_Ruby
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1

iron

  • use
  • AE
  • prevent maternal IDA
  • black tarry stool, constipation, GI upset
2

folic acid

  • use
  • ae
  • decrease birth defects
  • rash, pruritus, bronchospasm, general malaise, yellow urine
3

drug contraindicated in maternal constipation and why

stimulant laxatives. could have rebound constipation

4

terbutaline

  • MOA
  • USE
  • relax bronchial and uterine smooth muscle to prevent contraction
  • to decrease contraction in late 2nd and 3rd trimester
5

AE of terbutaline

  • maternal
  • fetus
  • dysrhythmias, anaphylaxis, chest pain, tachycardia
  • tachycardia, hypoglycemia
6

goal of terbutaline and magnesium sulfate

stop contraction to allow betamethasone to reach max benefit

7

magnesium sulfate

  • MOA
  • USE
  • AE
  • decrease uterine contraction, increase uterine perfusion
  • prevent preterm labor, stop seizures, lower BP in preeclampsia and eclampsia
  • deep tendon reflex, cardiac dysrhythmias
8

antido for magnesium sulfate

calcium gluconate n

9

nursing implication for magnesium sulfate

monitor levels, reduce levels in renal pts. contraindicated in MG

10

bethamethasone

  • MOA
  • USE
  • AE
  • surfactant production in fetal lungs
  • improve pulmonary maturity and function
  • seizures, vertigo, petechiae, ecchymosis
11

when is betamethasone given

24-48hrs before birth to mother

12

terbutaline is contraindicated in

PO administration. injection not for longterm

13

fentanyl

  • MOA
  • USE
  • AE
  • binds to CNS opiate receptors
  • pain relief during labor
  • dizziness, orthostatic hypotension, respiratory depression. antidote is narcan
14

dinoprostone

  • MOA
  • USE
  • AE
  • soften cervix and facilitate cervical dilation and effacement
  • stimulate uterine contraction
  • back pain, abnormal uterine contractions
15

dinoprostone is contraindicated in

use of other prostaglandins, uterine trauma, and fetal distress

16

oxytocin

  • MOA
  • USE
  • stimulates uterine contractions by increasing calcium concentration
  • induction or augment labor (only while in labor)
17

AE of oxytocin

  • maternal
  • fetal
  • cardiac dysrhythmias, HTN, uterine rupture, excess uterine stimulation
  • bradycardia, low Apgar score, neonatal jaundice
18

methylergonovine

  • MOA
  • USE
  • AE
  • increase uterine contraction force and frequency. GIVEN AFTER DELIVERY
  • treat maternal hemorrhage
  • cramping, dizziness, HTN if given IV
19

methylergonovine is contraindicated in

maternal sepsis, limit use with HTN, PVD