Immunodeficiencies

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created 8 years ago by chemistry_goo
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1

Immunological Competence

ability to produce an immune response after antigen exposure

2

Congenital

problems with embryological development of cells and/or organs

3

Severe Combined Immunodeficiency (SCI)

CONGENITAL
failure to develop humoral or cell-mediated immunity

4

HIV

infection with a virus that compromises immune function

5

Immunosuppressive agents

treatment or exposure to infection

6

Autoimmune diseases

-Loss of ability to tell self from foreign
-Production of autoantibodies and sensitized Tc cells
- NK cells may have mediated the disease via cytokines

7

Autoimmune disease cause

-T & B cell programming ineffective
-reduction of Ts activity or excessive stimuli of Th
-new self-antigens appear