Med Surg 2 Test 3: Giddens Glucose Regulation

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The nurse instructs a patient with type 1 diabetes mellitus to avoid which of the following drugs while taking insulin?

a. Furosemide (Lasix)

b. Dicumarol (Bishydroxycoumarin)

c. Reserpine (Serpasil)

d. Cimetidine (Tagamet)


Furosemide is a loop diuretic and can increase serum glucose levels; its use is contraindicated with insulin. Dicumarol, an anticoagulant; reserpine, an anti-hypertensive; and cimetidine, an H2 receptor antagonist, do not affect blood glucose levels.

REF: Page 135 |Page 141

OBJ: NCLEX® Client Needs Category: Physiological Integrity


When a diabetic patient asks about maintaining adequate blood glucose levels, which of the following statements by the nurse relates most directly to the necessity of maintaining blood glucose levels no lower than about 74 mg/dL?

a. “Glucose is the only type of fuel used by body cells to produce the energy needed for physiologic activity.”

b. “The central nervous system cannot store glucose and needs a continuous supply of glucose for fuel.”

c. “Without a minimum level of glucose circulating in the blood, erythrocytes cannot produce ATP.”

d. “The presence of glucose in the blood counteracts the formation of lactic acid and prevents acidosis.”


The brain cannot synthesize or store significant amounts of glucose; thus a continuous supply from the body’s circulation is needed to meet the fuel demands of the central nervous system.

REF: Page 134 OBJ: NCLEX® Client Needs Category: Physiological Integrity


The nurse associates which assessment finding in the diabetic patient with decreasing renal function?

a. Ketone bodies in the urine during acidosis

b. Glucose in the urine during hyperglycemia

c. Protein in the urine during a random urinalysis

d. White blood cells in the urine during a random urinalysis


Urine should not contain protein. Proteinuria in a diabetic heralds the beginning of renal insufficiency or diabetic nephropathy with subsequent progression to end stage renal disease. Chronic elevated blood glucose levels can cause renal hypertension and excess kidney perfusion with leakage from the renal vasculature. This leaking allows protein to be filtered into the urine.

REF: Page 138 OBJ: NCLEX® Client Needs Category: Physiological Integrity


What is the nurse’s best response about developing diabetes to the patient whose father has type 1 diabetes mellitus?

a. “You have a greater susceptibility for development of the disease because of your family history.”

b. “Your risk is the same as the general population, because there is no genetic risk for development of type 1 diabetes.”

c. “Type 1 diabetes is inherited in an autosomal dominant pattern. Therefore the risk for becoming diabetic is 50%.”

d. “Because you are a woman and your father is the parent with diabetes, your risk is not increased for eventual development of the disease. However, your brothers will become diabetic.”


Even though type 1 diabetes does not follow a specific genetic pattern of inheritance, those with one parent with type 1 diabetes are at an increased risk for development of the disease.

REF: Page 142 OBJ: NCLEX® Client Needs Category: Physiological Integrity


The nurse recognizes which patient as having the greatest risk for undiagnosed diabetes mellitus?

a. Young white man

b. Middle-aged African-American man

c. Young African-American woman

d. Middle-aged Native American woman


The highest incidence of diabetes in the United States occurs in Native Americans. With age, the incidence of diabetes increases in all races and ethnic groups.

REF: Page 137 OBJ: NCLEX® Client Needs Category: Physiological Integrity


A diabetic patient is brought into the emergency department unresponsive. The arterial pH is 7.28. Besides the blood pH, which clinical manifestation is seen in uncontrolled diabetes mellitus and ketoacidosis?

a. Decreased hunger sensation

b. Report of no urine output

c. Increased respiratory rate

d. Decreased thirst


Ketoacidosis decreases the pH of the blood, stimulating the respiratory control area of the brain to buffer the effects of the increasing acidosis. The rate and depth of respirations are increased (Kussmaul's respirations) to excrete more acids by exhalation. Usually polydipsia (increased thirst), polyphagia (increased hunger), and polyuria (increased urine output) are seen with hyperglycemia and ketoacidosis.

REF: Page 135 |Page 137

OBJ: NCLEX® Client Needs Category: Physiological Integrity


Which of the following would be included in the assessment of a patient with diabetes mellitus who is experiencing a hypoglycemic reaction? (Select all that apply.)

a. Tremors

b. Nervousness

c. Extreme thirst

d. Flushed skin

e. Profuse perspiration

f. Constricted pupils

ANS: A, B, E

When hypoglycemia occurs, blood glucose levels fall, resulting in sympathetic nervous system responses such as tremors, nervousness, and profuse perspiration. Dilated pupils would also occur, not constricted pupils. Extreme thirst, flushed skin, and constricted pupils are consistent with hyperglycemia.

REF: Page 135 OBJ: NCLEX® Client Needs Category: Physiological Integrity