Exer. Physiology test 3 acids and bases
Condition when your blood pH drops too low around 6.8.
condition when your blood pH gets too high around 7.8
Volatile acid contributing to hydrogen ions in blood
Sulfuric acid (metabolism of amino acids) and phosphoric acid (metabolism of phospholipids). Contributes to hydrogens in blood
Lactic acid (carbohydrate metabolism) and Acetoacetic acid (lipid metabolism). Contributes to hydrogen in blood.
How is carbonic acid produced in body?
Aerobic respiration of glucose
How is lactic acid produced in body?
Anaerobic respiration of glucose
How is sulfuric acid produced?
Oxidation of sulphur containing amino acids
How is phosphoric acid produced?
Hydrolysis of phosphoproteins and nucleoproteins
How are acidic ketone bodies produced?
Incomplete oxidation of fatty acids
What are the order of intracellular buffers?
Proteins 60%, bicarbonate 20-30%, and phosphate groups 10-20%
Why is hydrogen a problem?
Increased hydrogen ions=decrease in pH=decrease in calcium binding and decrease in PFK activity=reduction in contraction and slows glycolysis.
How is acid-base balance regulated?
When hydrogen ion increases and the pH decreases the lungs contribute because ventilation increases and blows off more CO2 increasing pH.
What are the main extracellular buffers
Hemoglobin and proteins are weak, but they are extracellular buffers. Bicarbonate is the biggest extracellular buffer.