Overview:
Overview:
Nucleic acids are either two things, single stranded ___ or double stranded ____.
RNA; DNA
Nucleic acids contain either DNA or RNA, which are required to code for what?
The proteins required for life.
How does the the information network work?
Info in DNA > RNA > Specific Proteins
>Nucleic Acids
>Nucleic Acids
What is the primary role of NUCLEIC ACIDS?
Store and transmit hereditary information.
What are nucleic acids MADE of? What creates them? Monomers called...
Nucleotides
Each Nucleotide has three components, what are they??
Pentose Sugar, Phosphate group, and a Nitrogen containing base.
What is a phosphodiester linkage?
A bond that joins two nucleotides within both DNA and RNA.
Which one, RNA or DNA, has one less Oxygen in the ribose sugar?
DNA
Each Nucleotide has three components, what are they??
Pentose Sugar, Phosphate group, and a Nitrogen containing base.
Whay is complementary base pairing?
The joining of Nitrogen containing bases in a DNA/RNA molecule.
What are the two categories of Nitrogen containing bases?
Purines and Pyrimidines.
What are the TWO Purines?
Adenine (A) and Guanine (G)
What are the TWO Pyrimidines?
Thymine (T) and Cytosine (C)
Thymine (T) and Cytosine (C), Adenine (A) and Guanine (G); Which pair with which IN DNA?
A and T ; G and C
IN RNA, the pairing is G and C, but A is NOT paired with T, it is paired with...
URACIL, A and U go together in RNA.
Why can complementary base pairing happen? (3 reasons)
1) There are sites for H bonding
2) The geometry of the sugar phosphate backbone allows A, T, C, and G to connect by facing them a certain way.
3) Purines are actually DOUBLE RINGED, and Pyrimidines are SINGLE RINGED
True or false: Because DNA has Thymine and RNA has Uracil, the two CANNOT complementary base pair with one another.
FALSE, they CAN.
What type of bond can contribute to the shape of the RNA molecule, Covalent or H bonding?
H bonding.
RNA is generally single stranded, but does it ever have double strands?
YES, when RNA folds it may become double stranded.
>Other roles of Nucleotides
>Other roles of Nucleotides
Besides DNA, what other "things" do Nucleotides help with?
ATP, GTP, and cAMP.
What does ATP do?
Acts as an energy transducer in biochemical reactions.
What about GTP?
It's an energy source and it will transfer info from environment to body.
And cAMP?
Involved in hormones and nervous system.
Who said that life CAN ONLY come from life? And in what time?
Louis pasteur (1660)
What kind of amino acids did scientists find in meteors?
Both left AND right.
What kind of RNA catalyze reactions?
Ribozymes
RNA could have acted as a catalyst for its own what and what?
Replication and protein synthesis.
Peptide linkages are catalyzed (sped up) by a what?
Ribozyme
In retroviruses, there is a protein that catalyzes for what?
RNA and DNA.
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