7 Gene Expression: Translation

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1

Which of the following statements is NOT true regarding the genetic code?

A) More than one codon can specify for an amino acid.

B) There is redundancy in the genetic code

C) Four nucleotides equal one codon

D) All of the above are correct

D

2

Why must the translation start site be specific?

A) It doesn’t have to be specific

B) Because there would be three different amino acid sequences that could be translated/synthesized from each mRNA strand if the start site wasn’t specific.

C) The genetic variation would be too low in the population if there was no specific start site.

D) b and c are correct

E) None of the above

B

3

Where does the wobble base pair occur between tRNA and mRNA? (select all that apply)

A) At the 3` codon position

B) At the 5` anticodon position

C) At the 5` codon position

D) At the 3` anticodon position

A, B

4

How is the correct amino acid attached to its tRNA?

A) Phosphorylation of tRNA recognizes the specific amino acid.

B) By a specific enzyme called aminoacyl-tRNA.

C) Hydrolyzation of tRNA recognizes the specific amino acid.

D) None of the above

B

5

In the synthesis of a protein, what is required in the first step (initiation)?

A) Peptidyl transferase

B) Stop codon

C) Special form of met-tRNA

D) All the above

C

6

During translation, a peptide bond is formed between the ______ of the incoming amino acid and the ______ of the last amino acid.

A) Carboxyl group, amino group

B) 5` end, 3`end

C) 3` end, 5` end

D) Amino group, carboxyl group

D

7

Which ribosomal subunit contains the peptidyl transferase component and acts as the ribozyme in both prokaryotes and eukaryotes?

A) Small ribosomal subunit

B) Large ribosomal subunit

C) 20S ribosomal subunit

D) None of the above

B

8

The ribosome translates mRNA in/from the ___ to ___ direction.

A) 5` to 3`

B) 3` to 5`

C) Amino terminus to the carboxy terminus

D) Carboxy terminus to the amino terminus

A

9

The ribosome synthesizes the protein in/from the ___ to ___ direction.

A) 5` to 3`

B) 3` to 5`

C) Amino terminus to the carboxy terminus

D) Carboxy terminus to the amino terminus

C

10

During the termination step of translation, a release factor binds and initiates the _____ of _______ to the polypeptide.

A) Addition, water

B) Cleavage, water

C) Addition, NH2

D) Cleavage, NH2

A