2 DNA Replication

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created 8 months ago by Jonathan_Miranda
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1

What is the function of helicase?

A) Copies DNA

B) Copies RNA

C) Initiates replication

D) Unwinds DNA

D

2

What is the purpose of G1 stage of the cell cycle?

A) Replication of chromosomes

B) Synthesize proteins needed for mitosis

C) Resting stage

D) Determining if the cell can now enter mitosis and divide

B

3

How many origins of replication are there in human DNA?

A) 1

B) 3

C) Many

D) 22

C

4

When is the origin of replication activated?

A) S-phase

B) G1

C) G2

D) G0

A

5

Which enzyme is responsible for proofreading each strand of DNA?

A) Helicase

B) DNA polymerase

C) Exonuclease

D) Ligase

B

6

Which of the following enzymes is NOT required for DNA replication?

A) Helicase

B) Ligase

C) primase

D) RNA polymerase

D

7

During DNA replication, an incoming deoxyribonucleoside triphosphate adds to the ____ end of the primer strand?

A) 3`

B) 5`

C) All of the above

D) None of the above

A

8

A nucleotide is composed of what parts?

A) Phosphate group, nitrogenous base, and a sugar

B) Five carbon sugar and nucleoside

C) Six carbon sugar, phosphate group, and a nucleoside

D) Five-carbon sugar and nitrogenous base

A

9

RNA primers are removed by what enzyme?

A) Nuclease

B) Exonuclease

C) DNA polymerase

D) Ligase

A

10

What is/are the purpose(s) of telomeres?

A) Protects the ends of DNA and prevent chromosomal ends from fusing

B) Block pain receptors

C) Synthesize RNA

D) Prevent chromosomal ends from fusing

A

11

Which of the following scenarios is NOT considered a mismatch error mutation in replication?

A) No repair of the mutation

B) Excision and repair of only the (old) template strand

C) Excision and repair of oly the newly synthesized strand

D) UV radiation

D

12

Which of following mutation repair mechanisms do NOT require two copies of DNA?

A) Base excision repair

B) Non-homologous and homologous end joining

C) Mismatch repair

D) Nucleotide excision repair

B

13

In DNA, replication is:

A) Initiated at the telomeres

B) Semi-conservative

C) Initiated de novo

D) Unidirectional

B

14

Which of the following is not required for DNA replication to occur?

A) Primase

B) Helicase

C) Polymerase

D) Meganuclease

D

15

Which of the following is NOT true regarding the origin of replication?

A) Replication bubble contains one replication fork

B) There are many origins of replication in human DNA

C) Rate of replication is determined by rate of initiation

D) Replication proceeds bi-directionally

A

16

DNA primase is responsible for which of the following?

A) Synthesis of a short RNA primer complementary to a ssDNA template

B) Separating double-stranded DNA into single strands

C) Synthesizing DNA

D) Proofreading DNA

A

17

DNA is separated into single strands prior to replication by which of the following?

A) DNA Primase

B) DNA Polymerase

C) Helicase

D) RNA Primase

C

18

In DNA, replication can only proceed in one direction. Which direction does DNA replication occur?

A) From the 3’ end to 5’ end

B) From the 5’ end to 3’ end

C) From the amino terminus to the carboxy terminus

D) From the carboxy terminus to the amino terminus

B

19

Why are Okazaki fragments produced during replication of DNA?

A) This occurs when DNA Primase accidentally places too many primers

B) This occurs when DNA polymerase skips portions of DNA, leaving empty spaces called Okazaki fragments

C) Because DNA is antiparallel and can only be synthesized in one direction

D) Because DNA replication never occurs continuously

C

20

RNA primers are removed by which enzyme?

A) Nuclease

B) DNA Polymerase

C) Helicase

D) RNA Primase

A

21

In a newly synthesized DNA strand, cytosine is accidentally replaced by adenine. In other words, adenine (on the newly synthesized strand) is incorrectly paired with guanine (on the template strand). If no repair is done to fix this error, what will result after one round of DNA replication?

A) 2 mutated DNA

B) 2 unchanged DNA

C) 2 mutated DNA and 1 unchanged DNA

D) 1 mutated DNA and 1 unchanged DNA

D

22

Of the following mutation repair mechanisms, which of the following does NOT require two copies of DNA?

A) Mismatch repair

B) Non-homologous and homologous end joining

C) Base excision repair

D) Nucleotide excision repair

B