Microscopic Anatomy and Organization of Skeletal Muscle

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1

Skeletal Muscle/Voluntary Muscle

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-attaches to the skeleton
-shapes the body and gives you the ability to move
-most of the muscle tissue in the body
-consciously controlled
-striated

2

Fibers

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-large, long cylindrical cells that makes up skeletal muscle
-multinucleated

3

Sarcolemma

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-membrane enclosing a striated muscle fiber

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Myofibrils

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-a contractile fibril of skeletal muscle
-made up of myofilaments

5

Myofilaments

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-composed of actin and myosin, which slide past each other during muscle activity to bring about shortening and contracting of the muscle cells

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Sarcomere

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-contractile units of muscle
-extends from the middle of one I band (its Z disc) to the middle of the next along the length of the myofibrils

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Transverse Tubule (t tubule)

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-deep invagination of the sarcolemma

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Terminal Cisterns

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-pairs of tranversely oriented channels that are confluent with the sarcotubules, which together with an intermediate T tubule constitute a triad of skeletal muscle

9

Triads

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-regions where the sarcoplasmic reticulum terminal borders a t tubule on each side.

10

Endomysium

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-delicate areolar connective tissue that encloses each muscle fiber

11

Perimysium

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-collagenic membrane surrounding several muscle fibers

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Fascicle

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-bundle of fibers

13

Epimysium

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- large number of fascicles bounded together by dense connective tissue

14

Deep Fascia

-coarser sheets of dense connective tissue that bind muscles into functional groups

15

Insertion

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-a muscles more movable attachment

16

Origin

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- a muscles immovable attachment

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Neuromuscular/Myoneural Junction

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- junction between an axon of a motor neuron and a muscle cell

18

Motor Unit

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-a neuron and all the muscle fibers it stimulates

19

Synaptic Cleft

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-small fluid-filled gap separating the neuron and muscle fiber membranes