An Introduction to Pharmacology, 6th edition: Hitner and Nagle
General term for undesirable and potentially harmful drug effect.
Drug that binds to a receptor and activates a physiologic response or drug action.
Drug that binds to a receptor and interferes with other drugs or substances from producing a drug effect.
Name that defines the chemical composition of a drug.
Situations or conditions when a certain drug should not be administered.
Drug that has the potential for abuse and thus is regulated by law.
A measurement of the amount of drug that is administered.
Intended or indicated uses for any drug.
Effective dose 50, or dose that will produce an effect that is half of the maximal response.
Nonproprietary name of a drug.
Lethal dose 50, or dose that will kill 50% of the laboratory animals tested.
Mechanism of action
Explanation of how a drug produces its effects.
Nonprescription, over-the-counter (OTC) drug
Drug that can be purchased without the services of a physician.
Study of drugs.
Measure of the strength, or concentration, of a drug required to produce a specific effect.
Drug for which dispensing requires a written or phone order that can only be issued by or under the direction of a licensed physician.
Specific cellular structure that a drug binds to and that produces a physiologic effect.
Drug effect other than the therapeutic effect that is usually undesirable but not harmful.
Site of action
Location within the body where a drug exerts its therapeutic effect, often a specific drug receptor.
Desired drug effect to alleviate some condition or symptom of disease.
Therapeutic Index (TI)
Ratio of the LD50 to the ED50 in animal studies.
Undesirable dru effect that implies drug poisoning; can be very harmful or life-threatening.
Patented proprietary name of a drug sold by a specific drug manufacturer; also referred to as the brand name.